IMAGE AND MOVIE GALLERY 2017-06-28T16:43:08+00:00

Two time-lapse movies of HOpr-GFP expression in the swi5 cells. GFP is expressed sporadically in a small fraction of cell cycles. For more information, see Zhang Q et al., (2013) PNAS, 110: 14012-14017.

FISH quantification of transcription level of two mRNAs in a divergent or convergent gene pair. For more information, see Yan C et al., (2016) Nature Communications, 7: 11099.

Induction of GAL1pr-GFP and GAL1pr-YFP at allelic location in diploid yeast cells. The activation time ofGAL1pr has large cell-to-cell variability. For more information, see Zhang DY & Bai L (2016) PNAS, 113:4428-33.

MET3pr-GFP expression in two strains of our reporter library. In the profile 2 strain, MET3 promoter is repressed by Sir2-mediated silencing, and in the profile 3 strain, MET3 promoter is repressed by transcriptional interference. The two mechanisms generate very different level of cell-to-cell variability. For more information, see Du MY et al., (2017) PLOS Genetics, 13(4):e1006736.